Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565896 | 1.00 | NPY5R (0.33) | NPY5RCA12CA1CA2CA7 | |
| SCHEMBL17090456 | 0.84 | GRIA1 (0.42) | NPY5RCA12CA1CA2CA7 | |
| SCHEMBL13565224 | 0.84 | GRIA1 (0.42) | NPY5RCA12CA1CA2CA7 | |
| SCHEMBL12881994 | 0.84 | HDAC6 (0.37) | — | |
| SCHEMBL10115013 | 0.84 | HDAC6 (0.37) | — | |
| SCHEMBL17090269 | 0.83 | NPY5R (0.36) | NPY5R | |
| SCHEMBL13565146 | 0.83 | NPY5R (0.36) | NPY5R | |
| SCHEMBL13565151 | 0.81 | NPY5R (0.36) | NPY5R | |
| SCHEMBL11935562 | 0.80 | KDM4E (0.35) | CA12CA1CA2CA7CA13 | |
| SCHEMBL11940091 | 0.80 | KDM4E (0.35) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |