Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565988 | 1.00 | NPY5R (0.35) | NPY5RALDH1A1WDR5NR3C1NR3C2 | |
| SCHEMBL13564951 | 0.86 | NPY5R (0.42) | NPY5RALDH1A1WDR5TRPV1BRD4 | |
| SCHEMBL17090541 | 0.86 | NPY5R (0.42) | NPY5RALDH1A1WDR5TRPV1BRD4 | |
| SCHEMBL10133498 | 0.86 | HDAC3 (0.46) | ALDH1A1WDR5MEN1KMT2A | |
| SCHEMBL10115040 | 0.86 | HDAC3 (0.46) | ALDH1A1WDR5MEN1KMT2A | |
| SCHEMBL17090442 | 0.85 | NPY5R (0.34) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL13565327 | 0.85 | NPY5R (0.34) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL17090204 | 0.84 | BRD4 (0.38) | NPY5RTRPV1POLBMAPTBRD4 | |
| SCHEMBL11935630 | 0.84 | NPY5R (0.35) | NPY5RALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL11941032 | 0.84 | NPY5R (0.35) | NPY5RALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |