Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090442 | 1.00 | NPY5R (0.34) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL11935630 | 0.91 | NPY5R (0.35) | NPY5RKDM4ELMNABRD4 | |
| SCHEMBL11941032 | 0.91 | NPY5R (0.35) | NPY5RKDM4ELMNABRD4 | |
| SCHEMBL17090445 | 0.89 | NPY5R (0.33) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL13565189 | 0.89 | NPY5R (0.33) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL17090277 | 0.86 | GRIA1 (0.37) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL13565977 | 0.86 | GRIA1 (0.37) | NPY5RKDM4EHTTLMNATRPV1 | |
| SCHEMBL10134490 | 0.86 | KMT2A (0.39) | KDM4ELMNATRPV1 | |
| SCHEMBL10115104 | 0.86 | KMT2A (0.39) | KDM4ELMNATRPV1 | |
| SCHEMBL17090546 | 0.85 | NPY5R (0.35) | NPY5RKDM4EHTTLMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |