Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935296 | 0.84 | NAMPT (0.44) | HDAC8PPARAFFAR1ROCK2 | |
| SCHEMBL13565969 | 0.84 | PPARA (0.41) | HDAC1HDAC8HDAC6PPARAFFAR1 | |
| SCHEMBL17090497 | 0.83 | HDAC1 (0.47) | HDAC1HDAC8HDAC6PPARAVNN1 | |
| SCHEMBL10116280 | 0.81 | HPGD (0.60) | HDAC8HDAC6MEN1KMT2APARP1 | |
| SCHEMBL13565492 | 0.80 | MAPT (0.47) | HDAC1HDAC8HDAC6PPARAMEN1 | |
| SCHEMBL13565590 | 0.80 | CTPS1 (0.45) | — | |
| SCHEMBL13566087 | 0.80 | RAB9A (0.48) | — | |
| SCHEMBL13564999 | 0.79 | CA1 (0.50) | MEN1KMT2AFFAR1 | |
| SCHEMBL13565010 | 0.79 | HPGD (0.55) | HDAC1VNN1MEN1KMT2AFFAR1 | |
| SCHEMBL13565011 | 0.79 | CA1 (0.53) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |