Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996017 | 0.80 | SHBG (0.37) | SHBGEPHX1 | |
| SCHEMBL170996 | 0.78 | SHBG (0.48) | SHBGEPHX1 | |
| SCHEMBL5672185 | 0.77 | SHBG (0.39) | SHBGEPHX1 | |
| SCHEMBL17835196 | 0.76 | SHBG (0.52) | SHBGEPHX1 | |
| SCHEMBL172667 | 0.76 | SHBG (0.52) | SHBGEPHX1 | |
| SCHEMBL28166542 | 0.70 | SHBG (0.45) | SHBGEPHX1ADH1CADH1A | |
| SCHEMBL27760925 | 0.70 | SHBG (0.44) | SHBGEPHX1ADH1CADH1A | |
| SCHEMBL18916708 | 0.69 | SHBG (0.43) | SHBGEPHX1 | |
| SCHEMBL12050070 | 0.68 | SHBG (0.37) | SHBGADH1CADH1A | |
| SCHEMBL23693003 | 0.68 | SHBG (0.38) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |