Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | MAOB | P27338 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032822 | 0.95 | HTR2C (0.33) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709450 | 0.95 | HTR2C (0.33) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL10033004 | 0.91 | PSEN1 (0.36) | SLC6A4SLC6A3PSEN1PSEN2APH1B | |
| SCHEMBL1709364 | 0.91 | HTR2C (0.33) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709499 | 0.91 | HTR2C (0.33) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709500 | 0.91 | HTR2C (0.33) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709404 | 0.90 | HTR2C (0.34) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709403 | 0.90 | HTR2C (0.34) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL1709443 | 0.90 | HTR2C (0.34) | HTR2CKDM1AMAOBMAOADPEP1 | |
| SCHEMBL10032987 | 0.89 | PSEN1 (0.39) | HTR2CMAOADPEP1MGLLHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |