Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032822 | 1.00 | HTR2C (0.33) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL1709402 | 0.95 | HTR2C (0.34) | HTR2CHTR2AHTR7HSD11B1DPEP1 | |
| SCHEMBL10032823 | 0.94 | HTR2C (0.34) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL1709404 | 0.94 | HTR2C (0.34) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL1709443 | 0.94 | HTR2C (0.34) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL1709403 | 0.94 | HTR2C (0.34) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL1709494 | 0.93 | HTR2C (0.35) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL10032990 | 0.90 | PSEN1 (0.38) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL2315989 | 0.90 | PSEN1 (0.38) | HTR2CHTR2AHTR7HSD11B1MCHR1 | |
| SCHEMBL10033139 | 0.90 | SIGMAR1 (0.39) | HTR2CHTR2AHTR7KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |