SCHEMBL170947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL171253	0.90	KMT2A (0.61)	NAMPTKDRMAPK14RETPLK4
	SCHEMBL13603809	0.85	KDR (0.61)	KDRMAPK14RETPLK4AURKA
	SCHEMBL171273	0.85	KDR (0.61)	NAMPTKDRMAPK14RETPLK4
	SCHEMBL15574673	0.83	KDR (0.57)	KDRMAPK14RETPLK4AURKA
	SCHEMBL13603520	0.83	BRAF (0.59)	KDRMAPK14RETPLK4AURKA
	SCHEMBL17000003	0.82	POLB (0.58)	KDRMAPK14RETPLK4AURKA
	SCHEMBL15573040	0.82	KDR (0.56)	KDRMAPK14RETPLK4AURKA
	SCHEMBL12020936	0.82	KDR (0.55)	KDRMAPK14RETPLK4AURKA
	SCHEMBL13603485	0.82	KDR (0.55)	NAMPTKDRMAPK14RETPLK4
	SCHEMBL13603624	0.82	KDR (0.55)	KDRMAPK14RETPLK4AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.