SCHEMBL1709487 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	2/20	0.40

▸	PSEN2	P49810	2/20	0.40

▸	APH1B	Q8WW43	2/20	0.40

▸	NCSTN	Q92542	2/20	0.40

▸	APH1A	Q96BI3	2/20	0.40

▸	PSENEN	Q9NZ42	2/20	0.40

▸	DGAT1	O75907	3/20	0.37

▸	SOAT1	P35610	1/20	0.37

▸	DPEP1	P16444	1/20	0.36

▸	MGLL	Q99685	1/20	0.35

▸	HTR2C	P28335	1/20	0.34

▸	FFAR4	Q5NUL3	3/20	0.34

▸	MAOA	P21397	1/20	0.34

▸	FFAR1	O14842	2/20	0.33

▸	P2RY14	Q15391	2/20	0.33

▸	HSD11B1	P28845	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10032987	0.99	PSEN1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10032990	0.94	PSEN1 (0.38)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2315989	0.94	PSEN1 (0.38)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2314367	0.92	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2317127	0.90	PSEN1 (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2315528	0.89	PSEN1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1709485	0.89	PSEN1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2317862	0.89	PSEN1 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1709402	0.88	HTR2C (0.34)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2319230	0.87	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012046771-A1	CYCLOALKANE COMPOUND	アステラス製薬株式会社 (JP)	2012-04-12	—	—	WO	disclosed