⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178337 | 1.00 | — | — | |
| SCHEMBL25404242 | 0.77 | — | — | |
| SCHEMBL872419 | 0.74 | HDAC8 (0.33) | — | |
| SCHEMBL28492128 | 0.73 | — | — | |
| SCHEMBL12805217 | 0.73 | — | — | |
| SCHEMBL9159764 | 0.73 | — | — | |
| SCHEMBL4024375 | 0.73 | — | — | |
| SCHEMBL6887027 | 0.73 | — | — | |
| SCHEMBL8270697 | 0.73 | — | — | |
| SCHEMBL16803989 | 0.72 | CHRNA7 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053723-A | Sulfamide derivative and its medicinal usage | EA制药株式会社 | 2018-12-21 | — | — | CN | disclosed |
| US-9828409-B2 | Bridged-cyclo-ProTides as prodrugs of therapeutic nucleosides and nucleotides | ZHONG MINGHONG (US) | 2017-11-28 | — | — | US | disclosed |
| US-20150266918-A1 | Bridged-Cyclo-ProTides as Prodrugs of Therapeutic Nucleosides and Nucleotides | ZHONG MINGHONG (US) | 2015-09-24 | — | — | US | disclosed |
| CN-104302645-A | Antibacterial compounds | BIOTA EUROPE LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-101039904-B | Is suitable for treating dopamine D3Heterocyclic compounds for receptor-modulated responsive disorders | ABBOTT GMBH & CO KG | 2014-09-24 | — | — | CN | disclosed |