⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536938 | 0.81 | — | — | |
| SCHEMBL6359901 | 0.79 | — | — | |
| SCHEMBL2391041 | 0.79 | RXFP1 (0.31) | — | |
| SCHEMBL28480373 | 0.78 | — | — | |
| SCHEMBL24760683 | 0.75 | EPHX2 (0.30) | — | |
| SCHEMBL21625979 | 0.75 | EPHX2 (0.30) | — | |
| SCHEMBL28519471 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL28875763 | 0.72 | MMP1 (0.34) | — | |
| SCHEMBL11182683 | 0.72 | KDM7A (0.32) | — | |
| SCHEMBL12415610 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| US-20220151916-A1 | SYSTEMS AND METHODS FOR BISTABLE OLIGOMERIC MACHINES | MOLECULAR MACHINES CORPORATION LTD. (IL) | 2022-05-19 | — | — | US | claimed |
| EP-3947492-A2 | SYSTEMS AND METHODS FOR BISTABLE OLIGOMERIC MACHINES | Avetisov, Vladik (RU) | 2022-02-09 | — | — | EP | claimed |
| US-10202366-B2 | Methods of promoting wound healing using CRM1 inhibitors | Karyopharm Therapeutics Inc. (US) | 2019-02-12 | — | — | US | claimed |
| US-20160170091-A1 | Photonic Crystal Microsphere | THE PROCTER & GAMBLE COMPANY | 2016-06-16 | — | — | US | claimed |
| US-12372070-B2 | Harvesting of thermal energy by nanomachines | MOLECULAR MACHINES CORPORATION LTD. (IL) | 2025-07-29 | — | — | US | disclosed |
| EP-4264046-B1 | HARVESTING OF THERMAL ENERGY BY NANOMACHINES | AVETISOV VLADIK (RU) | 2025-03-05 | — | — | EP | disclosed |
| US-12173697-B2 | Harvesting of thermal energy by nanomachines | MOLECULAR MACHINES CORPORATION LTD. (IL) | 2024-12-24 | — | — | US | disclosed |
| CN-115135307-B | Cell delivery vehicle | 株式会社ITO | 2024-11-22 | — | — | CN | disclosed |
| US-20240247645-A1 | HARVESTING OF THERMAL ENERGY BY NANOMACHINES | MOLECULAR MACHINES CORPORATION LTD. (IL) | 2024-07-25 | — | — | US | disclosed |
| EP-4374068-A1 | HARVESTING OF THERMAL ENERGY BY NANOMACHINES | Molecular Machines Corporation Ltd. (IL) | 2024-05-29 | — | — | EP | disclosed |
| US-20240060478-A1 | HARVESTING OF THERMAL ENERGY BY NANOMACHINES | MOLECULAR MACHINES CORPORATION LTD. (IL) | 2024-02-22 | — | — | US | disclosed |
| US-20160170091-A1 | Photonic Crystal Microsphere | THE PROCTER & GAMBLE COMPANY | 2016-06-16 | — | — | US | disclosed |
| US-20120088734-A1 | Cyclosporin Analogs | ALLERGAN, INC. (US) | 2012-04-12 | — | — | US | disclosed |
| US-20110130321-A1 | HEAT-SENSITIVE EMULSIONS | RHODIA OPERATIONS (FR) | 2011-06-02 | — | — | US | disclosed |
| US-20100173836-A1 | NOVEL MACROCYCLES | CYPRALIS LIMITED (GB) | 2010-07-08 | — | — | US | disclosed |
| US-20100173838-A1 | NOVEL PROCESS FOR THE PREPARATION OF CYCLOSPORIN DERIVATIVES | VISKOV CHRISTIAN | 2010-07-08 | — | — | US | disclosed |
| US-7678766-B2 | Process for the preparation of cyclosporin derivatives | AVENTIS PHARMA S.A. (FR) | 2010-03-16 | — | — | US | disclosed |
| US-7632807-B2 | Cyclosporin alkynes and their utility as pharmaceutical agents | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-20070213260-A1 | Novel process for the preparation of cyclosporin derivatives | AVENTIS PHARMA S.A. | 2007-09-13 | — | — | US | disclosed |