Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 7/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710017 | 1.00 | TAS2R14 (0.46) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL1363115 | 0.88 | TAS2R14 (0.51) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL1363920 | 0.88 | TAS2R14 (0.51) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL1291418 | 0.88 | TAS2R14 (0.51) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL12140104 | 0.88 | TAS2R14 (0.51) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL15712966 | 0.87 | TAS2R14 (0.47) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL13747842 | 0.87 | AR (0.48) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL1291656 | 0.81 | MEN1 (0.44) | — | |
| SCHEMBL4595644 | 0.81 | TAS2R14 (0.52) | TAS2R14ARCYP2C19ABCB11ALB | |
| SCHEMBL1291330 | 0.81 | AR (0.47) | TAS2R14AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047617-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2012-04-12 | — | — | WO | disclosed |