Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129360 | 1.00 | HSD17B10 (0.36) | HSD17B10KDM4EMAPTTHRBCHRM2 | |
| SCHEMBL9409739 | 0.80 | KDM4E (0.38) | KDM4EMAPTTHRBCHRM2CHRM1 | |
| SCHEMBL10367039 | 0.79 | POLB (0.37) | MAPTTHRBSMN1; SMN2MAPK1POLB | |
| SCHEMBL20337598 | 0.78 | ITGB1 (0.45) | HSD17B10KDM4EMAPTTHRBCHRM2 | |
| SCHEMBL31391829 | 0.78 | ITGB1 (0.45) | HSD17B10KDM4EMAPTTHRBCHRM2 | |
| SCHEMBL20337597 | 0.78 | ITGB1 (0.45) | HSD17B10KDM4EMAPTTHRBCHRM2 | |
| SCHEMBL17477578 | 0.78 | MEN1 (0.42) | KDM4E | |
| SCHEMBL17477576 | 0.78 | MEN1 (0.42) | KDM4E | |
| SCHEMBL20701900 | 0.77 | MAPK1 (0.39) | KDM4EMAPTTHRBMAPK1 | |
| SCHEMBL16026470 | 0.77 | HSD17B10 (0.39) | HSD17B10KDM4EMAPTTHRBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047617-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2012-04-12 | — | — | WO | disclosed |