⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27441255 | 0.89 | TSHR (0.39) | — | |
| SCHEMBL15223140 | 0.85 | TDP1 (0.39) | — | |
| SCHEMBL4267041 | 0.85 | ALDH1A1 (0.46) | — | |
| SCHEMBL7969593 | 0.84 | — | — | |
| SCHEMBL5682885 | 0.82 | TDP1 (0.62) | — | |
| SCHEMBL27277948 | 0.82 | ALDH1A1 (0.44) | — | |
| SCHEMBL31522116 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL1520911 | 0.81 | — | — | |
| SCHEMBL16850407 | 0.80 | TDP1 (0.39) | — | |
| SCHEMBL15028760 | 0.80 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-04-17 | — | — | US | disclosed |
| EP-4467547-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2024-11-27 | — | — | EP | disclosed |
| CN-118574818-A | Photochromic compound, naphthol derivative, curable composition, optical article, lens and spectacles | 株式会社德山 | 2024-08-30 | — | — | CN | disclosed |
| US-20170298001-A1 | TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF | CORSAIR PHARMA INC (US) | 2017-10-19 | — | — | US | disclosed |
| US-9637441-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-20 | — | — | US | disclosed |
| EP-2582676-B1 | TETRAHYDROQUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2016-12-14 | — | — | EP | disclosed |
| US-9394227-B1 | Treprostinil derivatives and compositions and uses thereof | Corsair Pharma, Inc. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9211343-B2 | siRNA conjugate and preparation method thereof | BIONEER CORPORATION (KR) | 2015-12-15 | — | — | US | disclosed |
| US-20150094457-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| US-20050159469-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2005-07-21 | — | — | US | disclosed |
| US-20030195363-A1 | Process for producing arylsulfenyl halide | AOKI TSUTOMU (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1072588-B1 | PROCESS FOR PRODUCING ARYLSULFENYL HALIDE | SHIONOGI & CO (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1072588-A1 | PROCESS FOR PRODUCING ARYLSULFENYL HALIDE | SHIONOGI & CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
| US-4894435-A | Polymerization of olefin/carbon monoxide with non-transition metal salt, bidentate p ligand and carboxylic acid ester | SHELL OIL COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4810774-A | CARBON MONOXIDE | SHELL OIL COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0254343-A1 | Catalyst compositions and process for preparing olefin/CO copolymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-01-27 | — | — | EP | disclosed |
| EP-0253416-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-01-20 | — | — | EP | disclosed |
| US-4261926-A | REACTION WITH KETONE IN PRESENCE OF PLATINUM HYDROGENATION CATALYST AND A PROMOTER ACID | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4063953-A | POLYETHERS, POLYEPICHLOROHYDRIN, VINYL CINNAMATES | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JA) | 1977-12-20 | — | — | US | disclosed |