SCHEMBL17101378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18075885	0.85	CYP2D6 (0.51)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL17101274	0.81	CYP2D6 (0.51)	CYP2D6ALDH1A1KMT2APOLBCHRM2
	SCHEMBL23744794	0.72	OPRL1 (0.61)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL2953304	0.72	CYP2D6 (0.55)	CYP2D6ALDH1A1TSHROPRL1POLB
	SCHEMBL11375974	0.71	KMT2A (0.60)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL11374272	0.71	CYP2D6 (0.53)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL17101429	0.71	CYP2D6 (0.51)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL11836107	0.71	KMT2A (0.56)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL11370652	0.71	CYP2D6 (0.60)	CYP2D6ALDH1A1TSHRKMT2AOPRL1
	SCHEMBL1313444	0.70	CYP2D6 (0.50)	CYP2D6ALDH1A1TSHRKMT2AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.