Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.58 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.58 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.58 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28065788 | 0.98 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL13542803 | 0.89 | KCNH2 (0.53) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL1956284 | 0.88 | GNAI3 (0.52) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL20233843 | 0.87 | GNAI3 (0.49) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL12745050 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL1462517 | 0.84 | KDM4E (0.43) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL13451334 | 0.82 | KDM4E (0.50) | KDM4ELMNAEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL14116863 | 0.82 | KDM4E (0.54) | KDM4ELMNAEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8682833 | 0.81 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL6247785 | 0.81 | GNAI3 (0.73) | GNAI3GNAO1GNAI1SOS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591220-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-114539134-A | Synthetic method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114539133-A | Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-103848777-A | Method for synthesizing N-(3-methoxy propyl)-4-amino-piperidine | YOUCARE PHARMACEUTICAL GROUP | 2014-06-11 | — | — | CN | claimed |
| CN-115703733-A | Preparation method of prucalopride intermediate | 山东新时代药业有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115197123-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 山东新时代药业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115197123-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 山东新时代药业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114591220-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591220-A | Preparation method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114539133-A | Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539133-A | Method for preparing prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539134-A | Synthetic method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539134-A | Synthetic method of prucalopride intermediate 1- (3-methoxypropyl) -4-piperidinamine | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108727351-A | A kind of process for purification of general reed Ka Bili | 鲁南制药集团股份有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-103848777-B | A kind of synthetic method of N-(3-methoxy-propyl)-4-amino piperidine | YUEKANG PHARMACEUTICAL GROUP CO., LTD. (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-103848777-B | A kind of synthetic method of N-(3-methoxy-propyl)-4-amino piperidine | YUEKANG PHARMACEUTICAL GROUP CO., LTD. (CN) | 2016-04-13 | — | — | CN | disclosed |
| WO-2015139332-A1 | METHOD FOR SYNTHESIZING N-(3-METHOXYLPROPYL)-4-AMINOPIPERIDINE | 悦康药业集团有限公司 | 2015-09-24 | — | — | WO | disclosed |
| CN-103848777-A | Method for synthesizing N-(3-methoxy propyl)-4-amino-piperidine | YOUCARE PHARMACEUTICAL GROUP | 2014-06-11 | — | — | CN | disclosed |