SCHEMBL1710316

SCHEMBL1710316

C=CCCCCC(CCCC=C)CCCCC=C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 4/20 0.41
MAPT P10636 2/20 0.37
ABCC4 O15439 1/20 0.37
TRPA1 O75762 3/20 0.36
USP2 O75604 2/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LPAR3 Q9UBY5 2/20 0.32
LMNA P02545 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14716699 0.94 TSHR (0.50) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL7526836 0.94 TSHR (0.50) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25178066 0.85 TSHR (0.61) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL25178137 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4LMNA
SCHEMBL9718823 0.85 TSHR (0.54) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25182470 0.83 TSHR (0.58) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25181767 0.83 TSHR (0.65) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL25182455 0.83 TSHR (0.58) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL21765896 0.83 TSHR (0.41) TSHRALDH1A1MAPTABCC4TRPA1
SCHEMBL25178120 0.83 TSHR (0.58) TSHRALDH1A1CYP3A4SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2915826-B1 POLYETHYLENE AND PROCESS FOR PRODUCTION THEREOF UNIVATION TECH LLC (US) 2024-02-28 EP disclosed
EP-3854825-A1 POLYMERS COMPRISING ETHYLENE AND C4 TO C14 ALPHA OLEFIN COMONOMERS ExxonMobil Chemical Patents Inc. (US) 2021-07-28 EP disclosed
EP-3583141-B1 GROUP 4 CATALYST COMPOUNDS AND PROCESS FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-02-17 EP disclosed
US-10696758-B2 Group 4 catalyst compounds and process for use thereof EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2020-06-30 US disclosed
CN-110325561-A 4th race's catalyst compounds and its application method 埃克森美孚化学专利公司 2019-10-11 CN disclosed
CN-106397636-B The dynamics of metalloscene catalyst is modulated 埃克森美孚化学专利公司 2019-09-20 CN disclosed
US-20180237559-A1 Group 4 Catalyst Compounds and Process for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2018-08-23 US disclosed
EP-2344333-B1 HIGH MIR LINEAR POLYETHYLENES AND COEXTRUDED FILMS THEREFROM UNIVATION TECH LLC (US) 2018-02-21 EP disclosed
CN-106397636-A Dynamic modulation of metallocene catalysts 埃克森美孚化学专利公司 2017-02-15 CN disclosed
CN-103857706-B Kinetic Modulation of Metallocene Catalysts 埃克森美孚化学专利公司 2016-09-28 CN disclosed
US-20120200010-A1 Polyethylene and Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-08-09 US disclosed
WO-2012096698-A2 POLYETHYLENE AND PROCESS FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-07-19 WO disclosed
US-20120101235-A1 Polyethylene and Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-04-26 US disclosed
US-20120101242-A1 Polyethylene and Process For Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-04-26 US disclosed
CN-102196906-A High MIR linear polye thylenes and coextruded films therefrom EXXONMOBIL CHEM PATENTS INC 2011-09-21 CN disclosed
EP-2344333-A1 HIGH MIR LINEAR POLYE THYLENES AND COEXTRUDED FILMS THEREFROM Exxonmobil Chemical Patents Inc. (US) 2011-07-20 EP disclosed
US-20110165395-A1 High MIR Linear Polyethylenes and Coextruded Films Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2011-07-07 US disclosed
WO-2010047709-A1 HIGH MIR LINEAR POLYE THYLENES AND COEXTRUDED FILMS THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-04-29 WO disclosed
US-20090297810-A1 Polyethylene Films and Process for Production Thereof UNIVATION TECHNOLOGIES, LLC 2009-12-03 US disclosed
WO-2009082546-A2 POLYETHYLENE FILMS AND PROCESS FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180237559-A1 Group 4 Catalyst Compounds and Process for Use Thereof CRBN, NOX3, CCR4 TSHR 3663/4885ALDH1A1 1607/4885MAPT 4605/4885
US-10696758-B2 Group 4 catalyst compounds and process for use thereof CRBN, NOX3, CCR4 TSHR 3663/4885ALDH1A1 1607/4885MAPT 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.