Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710232 | 0.93 | BDKRB2 (0.46) | BDKRB2CYP3A4 | |
| SCHEMBL1710442 | 0.85 | BDKRB2 (0.48) | BDKRB2CYP3A4 | |
| SCHEMBL13145882 | 0.81 | BDKRB2 (0.63) | BDKRB2CYP3A4 | |
| SCHEMBL12712321 | 0.81 | BDKRB2 (0.46) | BDKRB2CYP3A4 | |
| SCHEMBL14038595 | 0.80 | BDKRB2 (0.45) | BDKRB2CYP3A4 | |
| SCHEMBL1710569 | 0.79 | BDKRB2 (0.49) | BDKRB2 | |
| SCHEMBL1564137 | 0.79 | BDKRB2 (0.43) | BDKRB2CYP3A4 | |
| SCHEMBL13448509 | 0.78 | BDKRB2 (0.39) | BDKRB2CYP3A4 | |
| SCHEMBL1710187 | 0.78 | BDKRB2 (0.48) | BDKRB2CYP3A4 | |
| SCHEMBL13145867 | 0.77 | BDKRB2 (0.62) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344477-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010031589-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-03-25 | — | — | WO | claimed |
| EP-2344477-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010031589-A1 | SMALL MOLECULE BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-03-25 | — | — | WO | disclosed |