Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | LTA4H | P09960 | 6/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | BAX | Q07812 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979669 | 1.00 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL249169 | 0.84 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL18198 | 0.84 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL7811939 | 0.84 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL3175106 | 0.84 | ESR2 (1.00) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL133408 | 0.84 | ESR1 (0.58) | ESR1ESR2MEN1KMT2APDCD1 | |
| SCHEMBL25070443 | 0.83 | ESR1 (0.67) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL10445959 | 0.83 | ESR1 (0.67) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL8975027 | 0.81 | ESR2 (0.64) | ESR1ESR2MEN1KMT2ALTA4H | |
| SCHEMBL12804466 | 0.81 | ESR1 (0.73) | ESR1ESR2MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000659-B2 | Insulating layer-forming composition and use thereof | HILTI AKTIENGESELLSCHAFT (LI) | 2018-06-19 | — | — | US | disclosed |
| US-20150368509-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2015-12-24 | — | — | US | disclosed |
| US-20150275031-A1 | INSULATING LAYER-FORMING COMPOSITION AND USE THEREOF | HILTI AKTIENGESELLSCHAFT (LI) | 2015-10-01 | — | — | US | disclosed |