Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107150 | 1.00 | RAB9A (0.50) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17131988 | 1.00 | RAB9A (0.50) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17107172 | 0.87 | RAB9A (0.63) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17132001 | 0.87 | RAB9A (0.63) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17107170 | 0.87 | RAB9A (0.63) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17107179 | 0.85 | RAB9A (0.55) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17107177 | 0.85 | RAB9A (0.55) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17132022 | 0.85 | RAB9A (0.55) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17133140 | 0.84 | RAB9A (0.47) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL17107104 | 0.84 | RAB9A (0.50) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | claimed |
| US-9650369-B2 | Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease | XAVIER UNIVERSITY OF LOUISIANA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | MKI67, MIF, NUDC | RAB9A 1305/4885HSD17B10 1947/4885ALDH1A1 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.