Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.62 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113034 | 0.98 | GNAI3 (0.60) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL8424808 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL6391709 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL9598276 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL11179091 | 0.98 | GNAI3 (0.66) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL9441284 | 0.96 | GNAI3 (0.63) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| Bromide SCHEMBL28400706 | 0.96 | GNAI3 (0.63) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28332000 | 0.96 | GNAI3 (0.69) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| SCHEMBL10740911 | 0.96 | GNAI3 (0.63) | GNAI3GNAO1GNAI1TSHRALDH1A1 | |
| Bromide SCHEMBL28709122 | 0.94 | GNAI3 (0.61) | GNAI3GNAO1GNAI1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | GNAI3 926/4885GNAO1 805/4885GNAI1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.