SCHEMBL171087

SCHEMBL171087

CCOc1ccc(CS)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.67
IDO1 P14902 2/20 0.60
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
LTA4H P09960 2/20 0.50
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 1/20 0.47
DHFR P00374 1/20 0.46
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
PARP10 Q53GL7 1/20 0.45
RELA Q04206 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10610003 0.82 IDO1 (0.56) IDO1TSHRLTA4HSMN1; SMN2KDM4E
SCHEMBL10332452 0.82 IDO1 (0.56) IDO1LTA4HSMN1; SMN2LMNADHFR
SCHEMBL2215530 0.82 NQO1 (0.61) NQO1TSHRTDP1LTA4HSMN1; SMN2
1,4-Diethoxybenzene SCHEMBL124015 0.82 NQO1 (1.00) NQO1TSHRTDP1LTA4HSMN1; SMN2
1,4-Diethoxybenzene SCHEMBL28186701 0.82 NQO1 (1.00) NQO1TSHRTDP1LTA4HSMN1; SMN2
SCHEMBL2488793 0.80 NQO1 (0.74) NQO1TSHRTDP1LTA4HSMN1; SMN2
SCHEMBL31423 0.80 NQO1 (0.74) NQO1TSHRTDP1LTA4HSMN1; SMN2
1,4-Diethoxybenzene SCHEMBL11794798 0.79 NQO1 (0.93) NQO1TSHRTDP1LTA4HSMN1; SMN2
SCHEMBL9170059 0.79 NR5A1 (0.58) IDO1TSHRLTA4H
SCHEMBL15958746 0.78 NQO1 (0.70) NQO1TSHRTDP1LTA4HSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214497-B1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PHOTO-CURABLE DRY FILM AND METHOD FOR PRODUCING THE SAME, PATTERNING PROCESS, AND LAMINATE SHINETSU CHEMICAL CO (JP) 2019-08-07 EP disclosed
US-8263665-B2 Polymeric micelles for drug delivery INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-11 US disclosed
US-8258190-B2 Encapsulated contrast agents INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2426130-A1 PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 2012-03-07 EP disclosed
US-20100324259-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2010-12-23 US disclosed
US-20100159020-A1 POLYMERIC MICELLES FOR DRUG DELIVERY INTEZYNE TECHNOLOGIES, INC. (US) 2010-06-24 US disclosed
US-20100136063-A1 Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides UNIVERSITY OF SOUTH FLORIDA (US) 2010-06-03 US disclosed
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-04-09 US disclosed
EP-1651360-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME Valspar Sourcing, Inc. (US) 2006-05-03 EP disclosed
CN-1246412-C Adhesive for flexible printed circuit board TAIHONG SCIENCE & TECHNOLOGY C (CN) 2006-03-22 CN disclosed
WO-2005011880-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME VALSPAR SOURCING, INC. (US) 2005-02-10 WO disclosed
CN-1407049-A Adhesive for flexible printed circuit board TAIHONG SCIENCE & TECHNOLOGY C (CN) 2003-04-02 CN disclosed
CN-1057402-C Semiconductor packaging method TAIWAN GENERAL APPARATUS AND A (CN) 2000-10-11 CN disclosed
CN-1158497-A Semiconductor packaging method TAIWAN GENERAL APPTS AND APPLI (CN) 1997-09-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100136063-A1 Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides IAPP, APP, TTR NQO1 4224/4885IDO1 1649/4885TSHR 4273/4885
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS LIPA, LPXN, CD47 NQO1 3342/4885IDO1 3635/4885TSHR 2921/4885
US-20100159020-A1 POLYMERIC MICELLES FOR DRUG DELIVERY ABCB4, CLTB, CD47 NQO1 4610/4885IDO1 4616/4885TSHR 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.