Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 5/20 | 0.32 |
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489411 | 0.83 | STAT3 (0.40) | STAT3STAT1GUSBGRIA1CACNG8 | |
| SCHEMBL27609062 | 0.83 | STAT3 (0.40) | STAT3STAT1GUSBGRIA1CACNG8 | |
| 1,2-Dichlorobenzene SCHEMBL27856013 | 0.83 | STAT3 (0.41) | STAT3STAT1GUSBPTGESKDM4E | |
| SCHEMBL17112278 | 0.82 | STAT3 (0.55) | STAT3STAT1GUSBGRIA1CACNG8 | |
| SCHEMBL28698861 | 0.82 | STAT3 (0.39) | STAT3STAT1GUSBGRIA1CACNG8 | |
| SCHEMBL28156414 | 0.80 | STAT3 (0.38) | STAT3STAT1GUSBKDM4ENPC1 | |
| SCHEMBL869194 | 0.79 | STAT3 (0.38) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| Benzene SCHEMBL1525265 | 0.76 | STAT3 (0.47) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| Benzene SCHEMBL29181649 | 0.76 | STAT3 (0.47) | STAT3STAT1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9430673 | 0.76 | STAT3 (0.42) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122756-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144282-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2015-10-01 | — | — | WO | disclosed |