Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877921 | 0.88 | STAT3 (0.34) | STAT3STAT1 | |
| Phenol SCHEMBL27584348 | 0.87 | STAT3 (0.40) | STAT3STAT1HPGDALDH1A1KDM4E | |
| SCHEMBL30821407 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL6517023 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL29430977 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL6744970 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL9430673 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL15809 | 0.85 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL2552530 | 0.83 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL2552531 | 0.83 | STAT3 (0.39) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283356-C | Method for preparing porphyrin modified carbon nanotube-nano TiO2 photocatalyst | UNIV TIANJIN (CN) | 2006-11-08 | — | — | CN | claimed |
| CN-106716656-B | Composition is used in thermoelectric conversion element, N-shaped thermoelectric conversion layer and the formation of N-shaped thermoelectric conversion layer | 富士胶片株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-106716656-A | THERMOELECTRIC CONVERSION ELEMENT, n-TYPE THERMOELECTRIC CONVERSION LAYER AND COMPOSITION FOR FORMING n-TYPE THERMOELECTRIC CONVERSION LAYER | 富士胶片株式会社 | 2017-05-24 | — | — | CN | disclosed |
| US-20140243294-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | DUKE UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| US-8759324-B2 | Method of activation of oxazaphosphorines | DUKE UNIVERSITY (US) | 2014-06-24 | — | — | US | disclosed |
| US-20130172296-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | UNIV DUKE (US) | 2013-07-04 | — | — | US | disclosed |
| US-8399434-B2 | Method of activation of oxazaphosphorines | DUKE UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120077782-A9 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | DUKE UNIVERSITY (US) | 2012-03-29 | — | — | US | disclosed |
| US-20090318388-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | DUKE UNIVERSITY (US) | 2009-12-24 | — | — | US | disclosed |
| WO-2008073195-A2 | METHOD FOR ACTIVATION OF OXAZAPHOSPHORINES | DUKE UNIVERSITY (US) | 2008-06-19 | — | — | WO | disclosed |
| CN-1283356-C | Method for preparing porphyrin modified carbon nanotube-nano TiO2 photocatalyst | UNIV TIANJIN (CN) | 2006-11-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318388-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | PPOX, HMBS, OAT | STAT3 3574/4885STAT1 3297/4885HPGD 62/4885 |
| US-20140243294-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | PPOX, HMBS, OAT | STAT3 3574/4885STAT1 3297/4885HPGD 62/4885 |
| US-20120077782-A9 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | PPOX, HMBS, OAT | STAT3 3574/4885STAT1 3297/4885HPGD 62/4885 |
| US-20130172296-A1 | METHOD OF ACTIVATION OF OXAZAPHOSPHORINES | PPOX, HMBS, OAT | STAT3 3574/4885STAT1 3297/4885HPGD 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.