Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171128 | 0.82 | DRD4 (0.55) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL13490441 | 0.78 | DRD4 (0.51) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL105201 | 0.76 | DRD4 (0.53) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL13490649 | 0.76 | DRD4 (0.56) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL13592670 | 0.75 | DRD4 (0.53) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL13490438 | 0.74 | DRD4 (0.47) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL8214501 | 0.74 | NPC1 (0.56) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL15004236 | 0.72 | NPC1 (0.49) | DRD2HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL4589196 | 0.72 | DRD4 (0.57) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL6969008 | 0.71 | DRD4 (0.61) | DRD4DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |