Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044553 | 0.87 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8194797 | 0.87 | S1PR1 (0.64) | NPC1TP53RAB9AS1PR1S1PR3 | |
| SCHEMBL17825389 | 0.86 | S1PR1 (0.56) | MEN1KMT2AALDH1A1NPSR1S1PR1 | |
| SCHEMBL238334 | 0.85 | MEN1 (0.66) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28091799 | 0.85 | S1PR1 (0.53) | NPC1MEN1KMT2ATP53RAB9A | |
| SCHEMBL6585625 | 0.84 | DRD4 (0.63) | MEN1KMT2ANPSR1DRD4HDAC4 | |
| SCHEMBL2395932 | 0.84 | DRD4 (0.67) | DRD4HDAC4NAMPTHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL19066024 | 0.84 | MEN1 (0.65) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4676034 | 0.82 | HRH3 (0.64) | S1PR1S1PR3HRH3 | |
| SCHEMBL2395803 | 0.81 | LMNA (0.60) | MEN1KMT2ANPSR1DRD4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063173-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PIPERIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-26 | — | — | WO | disclosed |