Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 3/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171115 | 0.97 | CMA1 (0.51) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL172854 | 0.95 | ALDH1A1 (0.52) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL172529 | 0.88 | ALDH1A1 (0.61) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL171096 | 0.87 | CMA1 (0.52) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL172775 | 0.86 | ALDH1A1 (0.60) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL133701 | 0.86 | KMT2A (0.53) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL131981 | 0.86 | CMA1 (0.51) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL172580 | 0.86 | CMA1 (0.54) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL172461 | 0.86 | KMT2A (0.53) | CMA1CTSGKMT2AALDH1A1HPGD | |
| SCHEMBL132752 | 0.84 | KMT2A (0.51) | CMA1CTSGKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542667-B1 | UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC THERAPEUTICS INC (US) | 2012-03-07 | — | — | EP | disclosed |