Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102297 | 0.81 | MAPT (0.44) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL22723724 | 0.80 | ALDH1A1 (0.42) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL16722440 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL17121178 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL25481640 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL15910744 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL20719544 | 0.77 | KDM4E (0.34) | ALDH1A1POLBNQO2KDM4EL3MBTL1 | |
| SCHEMBL17102311 | 0.77 | NQO2 (0.41) | MAPTALDH1A1POLBNQO2KDM4E | |
| SCHEMBL17121092 | 0.74 | ALDH1A1 (0.36) | MAPTALDH1A1POLBKDM4ENSD2 | |
| SCHEMBL15910523 | 0.74 | MAPT (0.69) | MAPTALDH1A1POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015140054-A1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-24 | — | — | WO | disclosed |