Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.55 |
| ▸ | MAOA | P21397 | 15/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379063 | 0.82 | MAOB (0.58) | MAOBMAOAAOC3CA9 | |
| SCHEMBL23709902 | 0.80 | MAOB (0.52) | MAOBMAOAAOC3CA9 | |
| SCHEMBL12090647 | 0.80 | MAOB (0.67) | MAOBMAOAAOC3 | |
| SCHEMBL20715207 | 0.80 | MAOB (0.55) | MAOBMAOACA9 | |
| SCHEMBL11515388 | 0.79 | MAOB (0.50) | MAOB | |
| SCHEMBL11289877 | 0.77 | MAOB (0.53) | MAOBMAOAAOC3 | |
| SCHEMBL5478655 | 0.77 | MAOB (0.52) | MAOBMAOAAOC3 | |
| SCHEMBL703728 | 0.77 | MAOB (0.58) | MAOBMAOAAOC3CA9 | |
| SCHEMBL29724095 | 0.77 | MAOB (0.58) | MAOBMAOAAOC3CA9 | |
| SCHEMBL18850317 | 0.77 | MAOB (0.58) | MAOBMAOAAOC3CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344471-A1 | 7-PIPERIDINOALKYL-3,4-DIHYDROQUINOLONE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010038901-A1 | 7-PIPERIDINOALKYL-3,4-DIHYDROQUINOLONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-04-08 | — | — | WO | disclosed |