Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805290 | 0.90 | MAOB (0.49) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL28346887 | 0.84 | GAA (0.52) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL6981292 | 0.82 | AHR (0.51) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL6980695 | 0.81 | GAA (0.48) | MAOBGAAAHREIF2AK2GRIA1 | |
| SCHEMBL27691373 | 0.81 | MAOB (0.50) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL21604 | 0.80 | GAA (0.46) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL689457 | 0.79 | MAOB (0.62) | MAOBGAAAHREIF2AK2KMT2A | |
| SCHEMBL10828352 | 0.79 | AHR (0.51) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL1711697 | 0.79 | MAOB (0.55) | MAOB | |
| SCHEMBL14815914 | 0.79 | MAOB (0.52) | MAOBGAAPDE3BPDE3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29882-E | SALT FORMATION, REARRANGEMENT, DESULFURIZATION | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4056569-A | Ortho-[(alkylthio)(aminocarbonyl)methyl]anilines | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-3996264-A | Synthesis of oxindoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3972894-A | Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-08-03 | — | — | US | disclosed |