SCHEMBL17119528

SCHEMBL17119528

N#Cc1ccc2c3c(-c4ccccc4)c4c(cc5c6ccccc6c6cccc4c65)c(-c4ccccc4)c3c3cccc1c32

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.37
KDM4E B2RXH2 4/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 3/20 0.33
MCL1 Q07820 2/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PLK4 O00444 1/20 0.33
CHEK1 O14757 1/20 0.33
AURKA O14965 1/20 0.33
CHUK O15111 1/20 0.33
ROCK2 O75116 1/20 0.33
CHEK2 O96017 1/20 0.33
INSR P06213 1/20 0.33
CDK1 P06493 1/20 0.33
CSF1R P07333 1/20 0.33
PIM1 P11309 1/20 0.33
FGFR1 P11362 1/20 0.33
PRKACA P17612 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12961853 0.88 ALDH1A1 (0.42) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL12961859 0.88 ALDH1A1 (0.42) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL14139962 0.84 ALDH1A1 (0.36) ALDH1A1KDM4EGAAHPGDMCL1
SCHEMBL14139963 0.84 ALDH1A1 (0.36) ALDH1A1KDM4EGAAHPGDMCL1
SCHEMBL23081375 0.84 MEN1 (0.34) ALDH1A1FLT3LMNAMEN1KMT2A
SCHEMBL14242949 0.84 MEN1 (0.34) ALDH1A1KDM4EGAAHPGDMAOA
SCHEMBL25642252 0.84 ALDH1A1 (0.33) ALDH1A1KDM4EGAAHPGDPLK4
SCHEMBL14140050 0.84 MEN1 (0.34) ALDH1A1KDM4EGAAHPGDMAOA
SCHEMBL12449285 0.83 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL1062001 0.82 ALDH1A1 (0.41) ALDH1A1KDM4EGAAMAPTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9818957-B2 Organic light emitting element CANON KABUSHIKI KAISHA (JP) 2017-11-14 US disclosed
US-9705089-B2 Organic light emitting element CANON KABUSHIKI KAISHA (JP) 2017-07-11 US disclosed
US-20160079544-A1 ORGANIC LIGHT EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2016-03-17 US disclosed
US-20150270493-A1 ORGANIC LIGHT EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2015-09-24 US disclosed