Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352878 | 0.87 | CES2 (0.42) | DGAT1PPARDFLT1FLT4KDR | |
| SCHEMBL2554655 | 0.87 | CES2 (0.42) | DGAT1PPARDFLT1FLT4KDR | |
| SCHEMBL18661269 | 0.82 | CES2 (0.42) | GPR27ALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL20640043 | 0.81 | KAT6A (0.43) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30270028 | 0.81 | KAT6A (0.43) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20639833 | 0.79 | CES2 (0.42) | DGAT1PPARDALDH1A1KDM4EDGAT2 | |
| SCHEMBL14405776 | 0.74 | CES2 (0.41) | DGAT1PPARDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20639929 | 0.72 | GRM5 (0.40) | ALDH1A1KDM4EATML3MBTL1NPC1 | |
| SCHEMBL20639969 | 0.71 | CES2 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14332118 | 0.71 | CYP3A4 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143184-A1 | ANTIFUNGAL COMPOUND PROCESS | VIAMET PHARMACEUTICALS, INC. (US) | 2015-09-24 | — | — | WO | disclosed |