Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712648 | 0.81 | TSHR (0.39) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL1712731 | 0.80 | MEN1 (0.41) | TSHRMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12466328 | 0.76 | AOC3 (0.46) | ACP3AOC3PNMT | |
| SCHEMBL8330368 | 0.73 | ACP3 (0.38) | ACP3TSHRAOC3LMNAMEN1 | |
| SCHEMBL1711933 | 0.71 | SLC6A2 (0.35) | MEN1KMT2AIDO1ALDH1A1 | |
| SCHEMBL17860065 | 0.71 | TACR1 (0.44) | AOC3HPGDCYP2D6PNMT | |
| SCHEMBL4728454 | 0.71 | ACP3 (0.36) | ACP3AOC3 | |
| SCHEMBL7697736 | 0.69 | ACP3 (0.37) | ACP3TSHRAOC3MEN1KMT2A | |
| SCHEMBL15331162 | 0.69 | ACP3 (0.46) | ACP3TSHRAOC3LMNAMEN1 | |
| SCHEMBL9729576 | 0.69 | ACP3 (0.46) | ACP3TSHRAOC3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344460-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Galapagos N.V. (BE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |