Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712648 | 0.83 | TSHR (0.39) | IDO1TDO2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1712731 | 0.82 | MEN1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20495054 | 0.76 | MEN1 (0.34) | SLC6A2IDO1TDO2MEN1KMT2A | |
| SCHEMBL503318 | 0.75 | NR3C1 (0.38) | SLC6A2DRD3IDO1TDO2MEN1 | |
| SCHEMBL6388936 | 0.73 | HPGD (0.37) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5256023 | 0.72 | AOC3 (0.41) | IDO1TDO2ALDH1A1 | |
| SCHEMBL1711981 | 0.71 | ACP3 (0.36) | IDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL933449 | 0.69 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1906076 | 0.67 | MEN1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20495325 | 0.67 | PPARG (0.41) | MEN1KMT2ASLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344460-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Galapagos N.V. (BE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |