Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304562 | 0.79 | HSP90AB1 (0.41) | LMNAL3MBTL1PKMHSP90AB1 | |
| SCHEMBL25590520 | 0.75 | — | — | |
| SCHEMBL17119866 | 0.75 | CYP1A2 (0.36) | — | |
| SCHEMBL23141972 | 0.69 | HSP90AB1 (0.43) | PKMHSP90AB1 | |
| SCHEMBL1920514 | 0.69 | PKM (0.35) | PKMHSP90AB1 | |
| SCHEMBL1935371 | 0.69 | KMT2A (0.36) | PKMHSP90AB1 | |
| SCHEMBL30718870 | 0.69 | HSP90AB1 (0.43) | PKMHSP90AB1 | |
| SCHEMBL15256028 | 0.68 | MEN1 (0.34) | LMNA | |
| SCHEMBL13931366 | 0.67 | HSP90AB1 (0.36) | HSP90AB1 | |
| SCHEMBL13283451 | 0.65 | KMT2A (0.40) | LMNAPKMHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536410-B1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | MERCK SHARP & DOHME (US) | 2015-09-23 | — | — | EP | disclosed |