Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711295 | 0.89 | ESR1 (0.39) | ESR1ESR2METAP1ADORA1MAPT | |
| SCHEMBL16546079 | 0.84 | HSD17B1 (0.41) | ESR1ESR2ADORA1MAPTKDM4E | |
| SCHEMBL16546089 | 0.78 | KDR (0.33) | MAPTALDH1A1 | |
| SCHEMBL16546082 | 0.76 | NPC1 (0.32) | METAP1MAPTRAB9A | |
| SCHEMBL18998907 | 0.76 | NOTUM (0.40) | ESR1ESR2MAPTKDM4EALDH1A1 | |
| SCHEMBL13671139 | 0.76 | PARP10 (0.38) | ESR1ESR2METAP1MAPTKDM4E | |
| SCHEMBL12711373 | 0.76 | HSD17B1 (0.33) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12924298 | 0.75 | ESR1 (0.42) | ESR1ESR2MAPTKDM4EALDH1A1 | |
| SCHEMBL12924307 | 0.75 | ESR1 (0.42) | ESR1ESR2MAPTKDM4EALDH1A1 | |
| SCHEMBL16546095 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9147843-B2 | Organic semiconductor material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-29 | — | — | US | disclosed |