Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537014 | 0.92 | MAPT (0.39) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL8742216 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL2088482 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL4806523 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL3425033 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL3425032 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL4245664 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL435734 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL11335978 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 | |
| SCHEMBL2089612 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343974-A2 | NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS | Georgetown University (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010027641-A2 | NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS | GEORGETOWN UNIVERSITY (US) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010019963-A2 | NA CHANNELS, DISEASE, AND RELATED ASSAYS AND COMPOSITIONS | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |