SCHEMBL1712277

SCHEMBL1712277

COc1cccc(COc2cc[c]cc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.50
LMNA P02545 1/20 0.41
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.38
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GRM5 P41594 1/20 0.36
LPAR3 Q9UBY5 2/20 0.36
LPAR1 Q92633 1/20 0.36
FFAR1 O14842 2/20 0.36
MPO P05164 1/20 0.35
ADORA2A P29274 2/20 0.34
PDE5A O76074 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711764 0.81 KCNH2 (0.53) KCNH2LMNAMRGPRX4CYSLTR2CYSLTR1
SCHEMBL694568 0.81 KCNH2 (0.53) KCNH2LMNAKDM1AMAOAMAOB
SCHEMBL864563 0.78 KCNH2 (0.53) KCNH2LMNAMRGPRX4CYSLTR2CYSLTR1
SCHEMBL864107 0.78 KCNH2 (0.53) KCNH2LMNAMRGPRX4CYSLTR2CYSLTR1
SCHEMBL17541155 0.76 GRM5 (0.37) KCNH2NPC1RAB9ASMN1; SMN2GRM5
SCHEMBL15389495 0.76 KCNH2 (0.40) KCNH2KDM1AMAOAMAOBGRM5
SCHEMBL8477471 0.76 KDM1A (0.44) KCNH2KDM1AMAOAMAOBGRM5
SCHEMBL863712 0.75 KCNH2 (0.50) KCNH2LMNAMAOBMRGPRX4CYSLTR2
SCHEMBL23920187 0.74 GABRA5 (0.45) KCNH2KDM1AMAOAMAOBGRM5
SCHEMBL8485251 0.73 KDM1A (0.52) KCNH2KDM1AMAOAMAOBGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KCNH2 669/4885LMNA 3681/4885KDM1A 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.