SCHEMBL17124389

SCHEMBL17124389

C=C(C)[C@H]1CCC(COC(C)=O)=C[C@@H]1c1c(O)cc(C(C)(C)CCCC)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 11/20 0.49
CNR2 P34972 13/20 0.48
OPRM1 P35372 5/20 0.48
TRPV1 Q8NER1 3/20 0.46
GPR55 Q9Y2T6 3/20 0.46
CYP1A1 P04798 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2B6 P20813 2/20 0.46
SLC6A2 P23975 2/20 0.46
CYP2C19 P33261 2/20 0.46
SLC6A3 Q01959 2/20 0.46
TRPM8 Q7Z2W7 2/20 0.46
MLNR O43193 1/20 0.46
NR1I2 O75469 1/20 0.46
PDE9A O76083 1/20 0.46
ABCB11 O95342 1/20 0.46
LDHA P00338 1/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17124390 0.97 OPRM1 (0.49) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL17124385 0.96 OPRM1 (0.49) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681816 0.96 OPRM1 (0.49) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681864 0.96 OPRM1 (0.49) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL17124386 0.96 OPRM1 (0.49) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL17105801 0.92 CNR2 (0.43) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681865 0.92 CNR2 (0.43) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681813 0.92 CNR1 (0.44) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681814 0.91 CNR2 (0.43) CNR1CNR2OPRM1TRPV1GPR55
SCHEMBL15681817 0.91 CNR2 (0.43) CNR1CNR2OPRM1TRPV1GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9517989-B2 2-cycloalkyl resorcinol cannabinergic ligands NORTHEASTERN UNIVERSITY (US) 2016-12-13 US disclosed
US-20150274623-A1 2-CYCLOALKYL RESORCINOL CANNABINERGIC LIGANDS Northeastern Uiversity (US) 2015-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274623-A1 2-CYCLOALKYL RESORCINOL CANNABINERGIC LIGANDS CNR2, CNR1, OPRL1 CNR1 2/4885CNR2 1/4885OPRM1 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.