SCHEMBL171256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL171408	0.87	GRM5 (0.50)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL24265543	0.86	GRM5 (0.52)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL29574203	0.86	GRM5 (0.52)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL4010552	0.83	GRM5 (0.64)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL14544110	0.82	MAP3K5 (0.52)	GRM5PRMT1MEN1KMT2ALNPEP
	SCHEMBL171389	0.82	GRM5 (0.49)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL8315932	0.81	MEN1 (0.57)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL30796964	0.81	GRM5 (0.53)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL15247120	0.80	GRM5 (0.44)	GRM5PRMT1MEN1KMT2ANPSR1
	SCHEMBL13490443	0.80	GRM5 (0.44)	GRM5PRMT1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.