Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL3063890 | 1.00 | TSHR (0.59) | TSHRTDP1MAPK1MEN1KMT2A | |
| Propylene Glycol SCHEMBL8851056 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Tetraethylene Glycol SCHEMBL8850597 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Hexaethylene Glycol SCHEMBL16673171 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Propylene Glycol SCHEMBL8851429 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Triethylene Glycol SCHEMBL6869496 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Triethylene Glycol SCHEMBL8013235 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Propylene Glycol SCHEMBL3359839 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Triethylene Glycol SCHEMBL22077278 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A | |
| Triethylene Glycol SCHEMBL1073837 | 0.97 | MEN1 (0.61) | TSHRTDP1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221921-A | Highly weather-resistant unsaturated polyester resin and preparation method thereof | 山东飞源合成材料有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-117801206-A | Polyurethane foam material, polyurethane foam insole and preparation method of polyurethane foam insole | 万华化学集团股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-113980630-A | Preparation method of industrial band-aid based on silyl modified polymer | 张一平 | 2022-01-28 | — | — | CN | claimed |
| CN-110387032-A | A kind of polyester ether polylol, preparation method and its polyurethane elastomer of preparation | 万华化学集团股份有限公司 | 2019-10-29 | — | — | CN | claimed |
| WO-2008048548-A2 | LOW SHRINKAGE SHEET MOLDED COMPOSITE FORMULATIONS | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2008-04-24 | — | — | WO | claimed |
| US-20080090954-A1 | Low shrinkage sheet molded composite formulations | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2008-04-17 | — | — | US | claimed |
| US-20070219171-A1 | Transdermal Pharmaceutical Spray Formulations Comprising a Vp/Va Copolymer and a Non-Aquous Vehicle | WATERLEAD LIMITED (ZA) | 2007-09-20 | — | — | US | claimed |
| EP-0211722-B1 | SULFONATED AND SULFURIZED DETERGENT DISPERSANT ADDITIVES FOR LUBRICANT OILS | OROGIL (FR) | 1990-05-23 | — | — | EP | claimed |
| EP-0095813-A2 | Penetrating topical pharmaceutical compositions containing 9-(2-hydroxyethoxymethyl) guanine | THE PROCTER & GAMBLE COMPANY (US) | 1983-12-07 | — | — | EP | claimed |
| CN-118221921-A | Highly weather-resistant unsaturated polyester resin and preparation method thereof | 山东飞源合成材料有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240199913-A1 | METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-06-20 | — | — | US | disclosed |
| CN-118111972-A | Detection method and application of ethylene glycol and diethylene glycol in propylene glycol | 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） | 2024-05-31 | — | — | CN | disclosed |
| CN-117801206-A | Polyurethane foam material, polyurethane foam insole and preparation method of polyurethane foam insole | 万华化学集团股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-4309006-A1 | METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE | Tokyo Ohka Kogyo Co., Ltd. (JP) | 2024-01-24 | — | — | EP | disclosed |
| US-4395287-A | BLEND OF POLYOXYALKYLENE GLYCOLE | CANON KABUSHIKI KAISHA (JP) | 1983-07-26 | — | — | US | disclosed |
| US-4243759-A | POLYURETHANE FOAMS | MOBAY CHEMICAL CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4209609-A | INTERMEDIATES FOR POLYURETHANE FOAMS OF LOW FRIABILITY AND GOOD DIMENSIONAL STABILITY | MOBAY CHEMICAL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4083890-A | Unsaturated ester resin/monomer blend with hydroperoxide, vanadium compound and ketone peroxide for controlled gel time | THE DOW CHEMICAL COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4012559-A | Radiation curable coating composition and precoated metal having top coat based on the same | TORAY INDUSTRIES, INC (JA) | 1977-03-15 | — | — | US | disclosed |
| US-3967004-A | Method for the production of fiber-reinforced resin compounds | ODA KOUZOU | 1976-06-29 | — | — | US | disclosed |