⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198193 | 1.00 | — | — | |
| SCHEMBL14085156 | 1.00 | — | — | |
| SCHEMBL2111705 | 0.93 | — | — | |
| SCHEMBL12224195 | 0.93 | — | — | |
| SCHEMBL16711947 | 0.84 | — | — | |
| SCHEMBL644176 | 0.77 | — | — | |
| SCHEMBL6628953 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL6381448 | 0.75 | — | — | |
| SCHEMBL4523693 | 0.75 | — | — | |
| SCHEMBL17320217 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |
| EP-4013755-B1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2025-01-08 | — | — | EP | claimed |
| CN-111491918-B | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2023-10-24 | — | — | CN | claimed |
| CN-111491918-A | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2020-08-04 | — | — | CN | claimed |
| CN-104370909-B | Tricyclic compound | ABBVIE 公司 | 2018-09-11 | — | — | CN | claimed |
| CN-105384685-A | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2016-03-09 | — | — | CN | claimed |
| CN-102686566-A | Novel tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2012-09-19 | — | — | CN | claimed |
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-06-05 | — | — | US | claimed |
| US-20040220169-A1 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-11-04 | — | — | US | claimed |
| EP-0473387-A2 | Anti-fungal triazole derivatives, their preparation and uses | Sankyo Company Limited (JP) | 1992-03-04 | — | — | EP | claimed |
| WO-2024131265-A1 | COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2024-06-27 | — | — | WO | disclosed |
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | disclosed |
| EP-4306529-A2 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-3968999-B1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS INC (US) | 2023-12-27 | — | — | EP | disclosed |
| CN-111491918-B | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5929297-A | FORMING A MIXTURE OF DIMERS, TRIMERS AND OLIGOMERS BY CONTACTING AN ALPHA-OLEFIN WITH A CATALYST SYSTEM OF BORON TRIFLUORIDE, A PROTIC PROMOTER, AND A NITROGEN COMPOUND BEING AN AMIDE, UREA, IMIDE OR CARBAMATE | BP AMOCO CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5489606-A | FUNGICIDES, HUMAN, VETERNARY MEDICINE | SANKYO COMPANY, LIMITED (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5393769-A | Thio-, sulfinyl- or sulfonyl-substituted | SANKYO COMPANY, LIMITED (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0473387-A2 | Anti-fungal triazole derivatives, their preparation and uses | Sankyo Company Limited (JP) | 1992-03-04 | — | — | EP | disclosed |