SCHEMBL17128674

SCHEMBL17128674

[CH2][CH]Oc1ccc(O[CH][CH2])c(N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
THRB P10828 2/20 0.44
NR4A1 P22736 1/20 0.37
KDM4E B2RXH2 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
CYP3A4 P08684 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366855 0.81 ALDH1A1 (0.44) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL27901967 0.67 ALDH1A1 (0.63) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL29280402 0.63 MEN1 (0.50) MAPTALDH1A1MEN1KMT2ATHRB
Hydrochloric Acid SCHEMBL2585553 0.61 ALDH1A1 (1.00) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL28683526 0.61 ALDH1A1 (0.91) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL7295648 0.61 NR4A1 (0.56) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL15938210 0.61 ALDH1A1 (0.76) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL28854577 0.60 ALDH1A1 (0.44) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL28459787 0.60 ALDH1A1 (0.44) MAPTALDH1A1MEN1KMT2ATHRB
SCHEMBL22734442 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074814-A1 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE SUBLINO LIMITED (GB) 2024-04-11 WO disclosed
EP-2785797-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-9152006-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2015-10-06 US disclosed