Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | BRS3 | P32247 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713231 | 0.89 | BDKRB1 (0.84) | BDKRB1CNR1 | |
| SCHEMBL1713064 | 0.89 | BDKRB1 (0.56) | BDKRB1CNR1 | |
| SCHEMBL6185817 | 0.82 | BDKRB1 (0.65) | BDKRB1CNR1 | |
| SCHEMBL1713032 | 0.82 | BDKRB1 (0.72) | BDKRB1CNR1 | |
| SCHEMBL5362567 | 0.79 | BDKRB1 (0.74) | BDKRB1CNR1 | |
| SCHEMBL1713183 | 0.78 | BDKRB1 (0.69) | BDKRB1CNR1 | |
| SCHEMBL1713230 | 0.77 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL13449215 | 0.77 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL12476596 | 0.74 | BDKRB1 (0.69) | BDKRB1CNR1 | |
| SCHEMBL1712484 | 0.73 | BDKRB1 (0.72) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | disclosed |