Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476596 | 0.93 | BDKRB1 (0.69) | BDKRB1CNR1 | |
| SCHEMBL1713231 | 0.92 | BDKRB1 (0.84) | BDKRB1CNR1 | |
| SCHEMBL1713183 | 0.86 | BDKRB1 (0.69) | BDKRB1CNR1 | |
| SCHEMBL12477218 | 0.83 | BDKRB1 (0.71) | BDKRB1CNR1 | |
| SCHEMBL1712893 | 0.82 | BDKRB1 (0.71) | BDKRB1CNR1 | |
| Mk0686 SCHEMBL1713029 | 0.81 | BDKRB1 (1.00) | BDKRB1 | |
| Mk0686 SCHEMBL6183541 | 0.81 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL1713193 | 0.80 | BDKRB1 (0.71) | BDKRB1CNR1 | |
| SCHEMBL12477277 | 0.79 | BDKRB1 (0.72) | BDKRB1CNR1 | |
| SCHEMBL9947735 | 0.79 | BDKRB1 (0.53) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010031577-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | JERINI AG (DE) | 2010-03-25 | — | — | WO | claimed |
| EP-1501787-B1 | N-BIPHENYLMETHYL AMINOCYCLOALKANECARBOXAMIDE DERIVATIVES WITH A SUBSTIITUENT ON THE METHYL USEFUL AS BRADYKININ ANTAGONISTS | MERCK & CO INC (US) | 2005-11-09 | — | — | EP | claimed |