Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1712930

N.N.N.N.NC1(N)CCCCC1CC(=O)O.NC1(N)CCCCC1CC(=O)O.NC1(N)CCCCC1CC(=O)O.NC1(N)CCCCC1CC(=O)O

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.46
GRM5 P41594 1/20 0.46
GRM1 Q13255 1/20 0.46
ARG1 P05089 3/20 0.35
ARG2 P78540 2/20 0.35
SLC6A12 P48065 3/20 0.33
SLC6A11 P48066 3/20 0.33
SLC6A13 Q9NSD5 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
CACNA2D1 P54289 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC1A3 P43003 3/20 0.32
SLC1A2 P43004 3/20 0.32
SLC1A1 P43005 3/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21439966 0.74 GRM2 (0.38) GRM2GRM5GRM1SLC6A12SLC6A11
SCHEMBL11243667 0.74 GRM2 (0.39) GRM2GRM5GRM1ARG1ARG2
SCHEMBL6907841 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6914613 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6916720 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6225595 0.73 GRM2 (0.60) GRM2GRM5GRM1ARG1ARG2
SCHEMBL6914983 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6916012 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6916821 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19
SCHEMBL6909055 0.73 GRM2 (0.37) GRM2GRM5GRM1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344736-A1 METHOD FOR REDUCING NITRIC OXIDE IN THE EXHAUST GAS FLOW OF INTERNAL COMBUSTION ENGINES MAN Truck & Bus AG (DE) 2011-07-20 EP disclosed
WO-2010028775-A1 METHOD FOR REDUCING NITRIC OXIDE IN THE EXHAUST GAS FLOW OF INTERNAL COMBUSTION ENGINES MAN NUTZFAHRZEUGE AKTIENGESELLSCHAFT (DE) 2010-03-18 WO disclosed