Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.60 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.60 |
| ▸ | ARG1 | P05089 | 5/20 | 0.57 |
| ▸ | ARG2 | P78540 | 4/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.38 |
| ▸ | GRM8 | O00222 | 4/20 | 0.38 |
| ▸ | GRM6 | O15303 | 3/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225584 | 1.00 | GRM2 (0.60) | GRM2GRM5GRM1ARG1ARG2 | |
| SCHEMBL6225590 | 1.00 | GRM2 (0.60) | GRM2GRM5GRM1ARG1ARG2 | |
| SCHEMBL2906017 | 0.81 | ARG1 (0.57) | GRM2GRM5GRM1ARG1ARG2 | |
| SCHEMBL27198574 | 0.81 | ARG1 (0.57) | GRM2GRM5GRM1ARG1ARG2 | |
| SCHEMBL31440740 | 0.81 | ARG1 (0.57) | GRM2GRM5GRM1ARG1ARG2 | |
| SCHEMBL27198621 | 0.81 | ARG1 (0.57) | GRM2GRM5GRM1ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL1806885 | 0.79 | ARG1 (0.55) | GRM2GRM5GRM1ARG1ARG2 | |
| Bromide SCHEMBL27198559 | 0.79 | ARG1 (0.55) | GRM2GRM5GRM1ARG1ARG2 | |
| Bromide SCHEMBL27198716 | 0.79 | ARG1 (0.55) | GRM2GRM5GRM1ARG1ARG2 | |
| Bromide SCHEMBL27198603 | 0.79 | ARG1 (0.55) | GRM2GRM5GRM1ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581233-A2 | COMPOSITIONS AND METHODS FOR PAIN REDUCTION | RHODE ISLAND HOSPITAL (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004039247-A2 | COMPOSITIONS AND METHODS FOR PAIN REDUCTION | RHODE ISLAND HOSPITAL (US) | 2004-05-13 | — | — | WO | disclosed |