SCHEMBL1712977

SCHEMBL1712977

C=CC(CC(N)=O)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
FGFR4 P22455 1/20 0.35
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1712976 0.83 BLM (0.35) TSHRALDH1A1FGFR4SLC6A2SLC6A4
SCHEMBL24513224 0.83 BLM (0.35) TSHRALDH1A1FGFR4SLC6A2SLC6A4
SCHEMBL2679188 0.83 TSHR (0.40) TSHRALDH1A1FGFR4SLC6A2SLC6A4
SCHEMBL4112964 0.82
SCHEMBL24201150 0.77 KDM4E (0.30) ALDH1A1BLMCYP2C19
SCHEMBL24340602 0.76 BLM (0.41) TSHRALDH1A1FGFR4SLC6A2SLC6A4
SCHEMBL18850260 0.75
SCHEMBL459915 0.75
SCHEMBL293078 0.75
SCHEMBL29099376 0.75 KMT2A (0.38) TSHRALDH1A1FGFR4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934077-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/SA/LTD. (CH) 1999-08-11 EP claimed
WO-1998017310-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/S.A./LTD. (CH) 1998-04-30 WO claimed
US-4110244-A Photochromic plastic material AMERICAN OPTICAL CORPORATION (US) 1978-08-29 US claimed
US-4049846-A Photochromic plastic materials AMERICAN OPTICAL CORPORATION (US) 1977-09-20 US claimed
EP-3852801-A1 MUCOADHESIVE LIPIDIC DELIVERY SYSTEM University of Saskatchewan (CA) 2021-07-28 EP disclosed
WO-2020056524-A1 MUCOADHESIVE LIPIDIC DELIVERY SYSTEM UNIVERSITY OF SASKATCHEWAN (CA) 2020-03-26 WO disclosed
US-9588424-B2 Photosensitive resin composition for screen printing, photosensitive film, and screen plate SUNTYPE CO., LTD. (JP) 2017-03-07 US disclosed
EP-2344522-B1 COMBINATION ADJUVANT FORMULATION UNIV SASKATCHEWAN (CA) 2016-01-27 EP disclosed
US-20150212413-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR SCREEN PRINTING, PHOTOSENSITIVE FILM, AND SCREEN PLATE SUNTYPE CO., LTD. (JP) 2015-07-30 US disclosed
EP-2344522-A1 COMBINATION ADJUVANT FORMULATION The University of Saskatchewan (CA) 2011-07-20 EP disclosed
WO-2010043039-A1 COMBINATION ADJUVANT FORMULATION UNIVERSITY OF SASKATCHEWAN (CA) 2010-04-22 WO disclosed
US-6809165-B2 Method for producing polymers BASF AKTIENGESELLSCHAFT (DE) 2004-10-26 US disclosed
WO-1998017310-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/S.A./LTD. (CH) 1998-04-30 WO disclosed
CN-1031889-C Additives for diesel oil CHINESE PETRO CHEMICAL SALES C (CN) 1996-05-29 CN disclosed
US-4382800-A Free amine-containing polymeric dyes DYNAPOL (US) 1983-05-10 US disclosed
US-4339237-A Free amine-containing polymeric dyes DYNAPOL (US) 1982-07-13 US disclosed
US-4144252-A ANTHRAQUINONE DYES DYNAPOL (US) 1979-03-13 US disclosed
US-4110244-A Photochromic plastic material AMERICAN OPTICAL CORPORATION (US) 1978-08-29 US disclosed
US-4051138-A Water-soluble amine-linked polymeric colorants DYNAPOL (US) 1977-09-27 US disclosed
US-4049846-A Photochromic plastic materials AMERICAN OPTICAL CORPORATION (US) 1977-09-20 US disclosed