⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712977 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL19650483 | 0.74 | SLC7A5 (0.38) | — | |
| SCHEMBL1712976 | 0.71 | BLM (0.35) | — | |
| SCHEMBL24513224 | 0.71 | BLM (0.35) | — | |
| SCHEMBL2679188 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL21167276 | 0.71 | GRIK1 (0.50) | — | |
| SCHEMBL24340602 | 0.70 | BLM (0.41) | — | |
| SCHEMBL18850260 | 0.69 | — | — | |
| SCHEMBL459915 | 0.69 | — | — | |
| SCHEMBL10771743 | 0.69 | GRIK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226392-A1 | Phosphate-Binding Polymers for Oral Administration | GELTEX, INC. | 2009-09-10 | — | — | US | disclosed |
| US-7459151-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060171916-A1 | Phosphate-binding polymers for oral administration | HOLMES-FARLEY STEPHEN R | 2006-08-03 | — | — | US | disclosed |
| US-7014846-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2006-03-21 | — | — | US | disclosed |
| US-6858203-B2 | Method of making phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040191212-A1 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2004-09-30 | — | — | US | disclosed |
| US-20030133902-A1 | Method of making phosphate-binding polymers for oral administration | GELTEX PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| US-6509013-B1 | Water insoluble crosslinked allyl amine homo- or copolymer and carrier; removing phosphate from gastrointestinal tract; hyperphosphatemia | GELTEX PHARMACEUTICALS, INC. | 2003-01-21 | — | — | US | disclosed |
| US-5667775-A | TREATMENT OF HYPERPHOSPHATEMIA, ION EXCHANGING, CATIONIC POLYMERS, REMOVAL OF PHOSPHATE FROM GASTROINTESTINAL TRACT | GELTEX PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |