Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15700804 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL12845702 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL14473488 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL8392362 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL15632531 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL19958066 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL18814195 | 1.00 | CA12 (0.64) | CA12CA7CA14CA1CA2 | |
| SCHEMBL1679214 | 0.97 | CA12 (0.59) | CA12CA7CA14CA1CA2 | |
| SCHEMBL1434773 | 0.92 | — | — | |
| SCHEMBL2606444 | 0.91 | CA12 (0.54) | CA12CA7CA14CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790639-B1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2014-03-26 | — | — | EP | claimed |
| WO-2023219007-A1 | THERMOSETTING RESIN COMPOSITION, MOLDED ARTICLE, MOLDING MATERIAL FOR FIBER-REINFORCED COMPOSITE MATERIAL, AND FIBER-REINFORCED COMPOSITE MATERIAL | 東レ株式会社 | 2023-11-16 | — | — | WO | disclosed |
| EP-4198030-A1 | IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF | Shanghaitech University (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023078426-A1 | COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-05-11 | — | — | WO | disclosed |
| US-11524961-B2 | JAK kinase inhibitor and preparation method and use thereof | SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-12-13 | — | — | US | disclosed |
| EP-3328843-B1 | 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2022-10-26 | — | — | EP | disclosed |
| US-11331320-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2022-05-17 | — | — | US | disclosed |
| CN-108690006-B | Compound and application thereof in anti-AML (AML) drugs | 中国药科大学 | 2022-02-18 | — | — | CN | disclosed |
| WO-2022033548-A1 | IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF | 上海科技大学 | 2022-02-17 | — | — | WO | disclosed |
| CN-113089005-B | Electrochemical synthesis method of sulfamide | 华南理工大学 | 2022-02-15 | — | — | CN | disclosed |
| WO-2006048546-A1 | USE OF AN AROMATIC CARBOXYLIC ACID IN AN ASYMMETRIC CATALYSIS REACTION | SHASUN PHARMA SOLUTIONS LIMITED (GB) | 2006-05-11 | — | — | WO | disclosed |
| CN-1633412-A | Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative | SERVIER LAB (FR) | 2005-06-29 | — | — | CN | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-6706748-B2 | USE AS MICROBICIDES | NIHON BAYER AGROCHEM, K.K. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030220197-A1 | Isothiazole derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-1284970-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | disclosed |
| US-4402980-A | FUNGICIDES; WOOD PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
| EP-0027622-A1 | Cycloalkyl-sulfon amides, process for their preparation, and their microbicidal use | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220197-A1 | Isothiazole derivatives | IRF3, MSR1, ARG1 | CA12 4198/4885CA7 3428/4885CA14 3414/4885 |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | CA12 4177/4885CA7 3016/4885CA14 4173/4885 |
| US-11524961-B2 | JAK kinase inhibitor and preparation method and use thereof | JAK1, JAK2, JAK3 | CA12 4541/4885CA7 2855/4885CA14 4203/4885 |
| US-11331320-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | JAK3, JAK1, JAK2 | CA12 4862/4885CA7 4758/4885CA14 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.